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Hedgehog Signaling: An Achilles’ Heel in Cancer
Hedgehog signaling pathway originally identified in the fruit fly Drosophila is an evolutionarily conserved signaling mechanism with crucial roles in embryogenesis, growth and patterning. It exerts its biological effect through a signaling mechanism that terminates at glioma-associated oncogene (GLI...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664200/ https://www.ncbi.nlm.nih.gov/pubmed/31352196 http://dx.doi.org/10.1016/j.tranon.2019.07.004 |