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Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial

Psychological distress is common in lung cancer patients with a poor prognosis. The present study aims to investigate the efficacy of collaborative care for patients with newly diagnosed inoperable lung cancer in South Korea. The study is a three-arm parallel-groups nonrandomized clinical trial with...

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Autores principales: Kim, Seon-Young, Kim, Sung-Wan, Shin, Il-Seon, Oh, In-Jae, Park, Cheol-Kyu, Kim, Young-Chul, Kim, Jae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664219/
https://www.ncbi.nlm.nih.gov/pubmed/31352737
http://dx.doi.org/10.30773/pi.2019.03.09
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author Kim, Seon-Young
Kim, Sung-Wan
Shin, Il-Seon
Oh, In-Jae
Park, Cheol-Kyu
Kim, Young-Chul
Kim, Jae-Min
author_facet Kim, Seon-Young
Kim, Sung-Wan
Shin, Il-Seon
Oh, In-Jae
Park, Cheol-Kyu
Kim, Young-Chul
Kim, Jae-Min
author_sort Kim, Seon-Young
collection PubMed
description Psychological distress is common in lung cancer patients with a poor prognosis. The present study aims to investigate the efficacy of collaborative care for patients with newly diagnosed inoperable lung cancer in South Korea. The study is a three-arm parallel-groups nonrandomized clinical trial with an active arm that includes distressed patients who receive collaborative care, one comparison arm that includes distressed patients who receive enhanced usual care, and another comparison arm that includes non-distressed patients. In total, 267 consecutive patients newly diagnosed with medically inoperative lung cancer will be recruited. The primary outcomes are the changes in Hospital Anxiety and Depression Scale-depression and the Distress Thermometer at 12 and 32 weeks after enrollment. Sub-analyses of patients in the active arm of the study will include a comparison of the efficacy of a combination of oral antidepressant (escitalopram) treatment and collaborative care versus that of collaborative care alone.
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spelling pubmed-66642192019-07-31 Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial Kim, Seon-Young Kim, Sung-Wan Shin, Il-Seon Oh, In-Jae Park, Cheol-Kyu Kim, Young-Chul Kim, Jae-Min Psychiatry Investig Study Protocol Psychological distress is common in lung cancer patients with a poor prognosis. The present study aims to investigate the efficacy of collaborative care for patients with newly diagnosed inoperable lung cancer in South Korea. The study is a three-arm parallel-groups nonrandomized clinical trial with an active arm that includes distressed patients who receive collaborative care, one comparison arm that includes distressed patients who receive enhanced usual care, and another comparison arm that includes non-distressed patients. In total, 267 consecutive patients newly diagnosed with medically inoperative lung cancer will be recruited. The primary outcomes are the changes in Hospital Anxiety and Depression Scale-depression and the Distress Thermometer at 12 and 32 weeks after enrollment. Sub-analyses of patients in the active arm of the study will include a comparison of the efficacy of a combination of oral antidepressant (escitalopram) treatment and collaborative care versus that of collaborative care alone. Korean Neuropsychiatric Association 2019-07 2019-07-25 /pmc/articles/PMC6664219/ /pubmed/31352737 http://dx.doi.org/10.30773/pi.2019.03.09 Text en Copyright © 2019 Korean Neuropsychiatric Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Study Protocol
Kim, Seon-Young
Kim, Sung-Wan
Shin, Il-Seon
Oh, In-Jae
Park, Cheol-Kyu
Kim, Young-Chul
Kim, Jae-Min
Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title_full Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title_fullStr Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title_full_unstemmed Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title_short Collaborative Care to Relieve Psychological Distress in Patients with Medically Inoperable Lung Cancer: Design and Rationale for a Clinical Trial
title_sort collaborative care to relieve psychological distress in patients with medically inoperable lung cancer: design and rationale for a clinical trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664219/
https://www.ncbi.nlm.nih.gov/pubmed/31352737
http://dx.doi.org/10.30773/pi.2019.03.09
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