Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery

Malignant hyperthermia (MH) is a rare pharmacogenic disorder of skeletal muscle calcium regulation, resulting from general anesthesia that can be fatal. Most cases are caused by administration of volatile anesthetics or depolarizing muscle relaxants. It has been generally reported that both of sevof...

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Autores principales: Ferhi, Fehmi, Dardour, Leïla, Tej, Amel, Kebaili, Raoudha, M'aaref, Sarra, Jazia, Khaled Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664270/
https://www.ncbi.nlm.nih.gov/pubmed/31384166
http://dx.doi.org/10.1016/j.sjopt.2018.10.002
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author Ferhi, Fehmi
Dardour, Leïla
Tej, Amel
Kebaili, Raoudha
M'aaref, Sarra
Jazia, Khaled Ben
author_facet Ferhi, Fehmi
Dardour, Leïla
Tej, Amel
Kebaili, Raoudha
M'aaref, Sarra
Jazia, Khaled Ben
author_sort Ferhi, Fehmi
collection PubMed
description Malignant hyperthermia (MH) is a rare pharmacogenic disorder of skeletal muscle calcium regulation, resulting from general anesthesia that can be fatal. Most cases are caused by administration of volatile anesthetics or depolarizing muscle relaxants. It has been generally reported that both of sevoflurane and succinylcholine can induce the delayed onset of MH. Here, we report a case of malignant hyperthermia in a four-year-old girl during anesthesia induction for unilateral congenital ptosis surgery, two minutes after sevoflurane and succinylcholine administration. The crisis was atypical but early recognized and managed by administration of dantrolene with symptomatic treatment.
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spelling pubmed-66642702019-08-05 Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery Ferhi, Fehmi Dardour, Leïla Tej, Amel Kebaili, Raoudha M'aaref, Sarra Jazia, Khaled Ben Saudi J Ophthalmol Article Malignant hyperthermia (MH) is a rare pharmacogenic disorder of skeletal muscle calcium regulation, resulting from general anesthesia that can be fatal. Most cases are caused by administration of volatile anesthetics or depolarizing muscle relaxants. It has been generally reported that both of sevoflurane and succinylcholine can induce the delayed onset of MH. Here, we report a case of malignant hyperthermia in a four-year-old girl during anesthesia induction for unilateral congenital ptosis surgery, two minutes after sevoflurane and succinylcholine administration. The crisis was atypical but early recognized and managed by administration of dantrolene with symptomatic treatment. Elsevier 2019 2018-10-19 /pmc/articles/PMC6664270/ /pubmed/31384166 http://dx.doi.org/10.1016/j.sjopt.2018.10.002 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Ferhi, Fehmi
Dardour, Leïla
Tej, Amel
Kebaili, Raoudha
M'aaref, Sarra
Jazia, Khaled Ben
Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title_full Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title_fullStr Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title_full_unstemmed Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title_short Malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
title_sort malignant hyperthermia in a 4-year-old girl during anesthesia induction with sevoflurane and succinylcholine for congenital ptosis surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664270/
https://www.ncbi.nlm.nih.gov/pubmed/31384166
http://dx.doi.org/10.1016/j.sjopt.2018.10.002
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