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Inhibitor of DNA binding 1 (Id1) mediates stemness of colorectal cancer cells through the Id1-c-Myc-PLAC8 axis via the Wnt/β-catenin and Shh signaling pathways

BACKGROUND: Inhibitor of DNA binding 1 (Id1) is upregulated in multiple cancers, and Id1overexpression correlates with cancer aggressiveness and poor clinical outcomes in cancer patients. However, its roles in cancer stem-like cells (CSCs) and epithelial-mesenchymal transition (EMT) are still elusiv...

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Detalles Bibliográficos
Autores principales: Sun, Yanxia, Lai, Xiaolan, Yu, Yue, Li, Jieyu, Cao, Lei, Lin, Wansong, Huang, Chuanzhong, Liao, Jinrong, Chen, Wei, Li, Chao, Yang, Chunkang, Ying, Mingang, Chen, Qiang, Ye, Yunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664424/
https://www.ncbi.nlm.nih.gov/pubmed/31440083
http://dx.doi.org/10.2147/CMAR.S207167

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