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Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117/CT71/vanB –clone in the Rhine-Main metropolitan area of Germany

Whole-genome sequencing analysis of Vancomycin-resistant Enterococcus faecium isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common vanB chromosomal insertion site. This indicates circulation of a single VRE clone in...

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Detalles Bibliográficos
Autores principales: Falgenhauer, Linda, Fritzenwanker, Moritz, Imirzalioglu, Can, Steul, Katrin, Scherer, Marlene, Heudorf, Ursel, Chakraborty, Trinad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664515/
https://www.ncbi.nlm.nih.gov/pubmed/31384433
http://dx.doi.org/10.1186/s13756-019-0573-8
Descripción
Sumario:Whole-genome sequencing analysis of Vancomycin-resistant Enterococcus faecium isolates from the Frankfurt metropolitan region revealed that 78/94 isolates were MLST type ST117, cgMLST complex type CT71 with a common vanB chromosomal insertion site. This indicates circulation of a single VRE clone in a catchment area of 5,000-km(2) with 3 million inhabitants. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13756-019-0573-8) contains supplementary material, which is available to authorized users.