TGF-β1 reduces the oxidative stress-induced autophagy and apoptosis in rat annulus fibrosus cells through the ERK signaling pathway

BACKGROUND: The aim of this study is to explore the effects of TGF-β1 on autophagy and apoptosis induced by exogenous hydrogen peroxide (H(2)O(2)) in annulus fibrosus (AF) cells and possible signal pathways involved in this process. METHODS: AF cells were isolated from rat lumbar discs and subjected...

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Detalles Bibliográficos
Autores principales: Ni, Binbin, Shen, Hao, Wang, Wei, Lu, Hua, Jiang, Leisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664534/
https://www.ncbi.nlm.nih.gov/pubmed/31358027
http://dx.doi.org/10.1186/s13018-019-1260-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664534/
https://www.ncbi.nlm.nih.gov/pubmed/31358027
http://dx.doi.org/10.1186/s13018-019-1260-4

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