Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X-chromosome inactivation

BACKGROUND: Associations between X-inactive transcript (Xist)–long noncoding RNA (lncRNA) and chromatin are critical intermolecular interactions in the X-chromosome inactivation (XCI) process. Despite high-resolution analyses of the Xist RNA-binding sites, specific interaction sequences are yet to b...

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Detalles Bibliográficos
Autores principales: Matsuno, Yoko, Yamashita, Takefumi, Wagatsuma, Michiru, Yamakage, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664574/
https://www.ncbi.nlm.nih.gov/pubmed/31384315
http://dx.doi.org/10.1186/s13100-019-0173-4

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