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Histone deacetylase 1 induced by neddylation inhibition contributes to drug resistance in acute myelogenous leukemia

OBJECTIVE: This study aimed to investigate the function and mechanism of neddylation of HDAC1 underlying drug resistance of AML cells. METHODS: Evaluation experiments of effects of HDAC1 on drug resistance of AML cells were performed with AML cell transfected with constructs overexpressing HDAC1 or...

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Detalles Bibliográficos
Autores principales:	Lai, Qiu-yu, He, Ying-zhi, Peng, Xiong-wen, Zhou, Xuan, Liang, Dan, Wang, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664585/ https://www.ncbi.nlm.nih.gov/pubmed/31358016 http://dx.doi.org/10.1186/s12964-019-0393-8

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