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Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned
BACKGROUND: Malaria transmission is high in western Kenya and the asymptomatic infected population plays a significant role in driving the transmission. Mathematical modelling and simulation programs suggest that interventions targeting asymptomatic infections through mass testing and treatment (MTa...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664589/ https://www.ncbi.nlm.nih.gov/pubmed/31357997 http://dx.doi.org/10.1186/s12936-019-2896-6 |
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author | Odero, Norbert Awino Samuels, Aaron M. Odongo, Wycliffe Abong’o, Bernard Gimnig, John Otieno, Kephas Odero, Christopher Obor, David Ombok, Maurice Were, Vincent Sang, Tony Hamel, Mary J. Kachur, S. Patrick Slutsker, Laurence Lindblade, Kim A. Kariuki, Simon Desai, Meghna |
author_facet | Odero, Norbert Awino Samuels, Aaron M. Odongo, Wycliffe Abong’o, Bernard Gimnig, John Otieno, Kephas Odero, Christopher Obor, David Ombok, Maurice Were, Vincent Sang, Tony Hamel, Mary J. Kachur, S. Patrick Slutsker, Laurence Lindblade, Kim A. Kariuki, Simon Desai, Meghna |
author_sort | Odero, Norbert Awino |
collection | PubMed |
description | BACKGROUND: Malaria transmission is high in western Kenya and the asymptomatic infected population plays a significant role in driving the transmission. Mathematical modelling and simulation programs suggest that interventions targeting asymptomatic infections through mass testing and treatment (MTaT) or mass drug administration (MDA) have the potential to reduce malaria transmission when combined with existing interventions. OBJECTIVE: This paper describes the study site, capacity development efforts required, and lessons learned for implementing a multi-year community-based cluster-randomized controlled trial to evaluate the impact of MTaT for malaria transmission reduction in an area of high transmission in western Kenya. METHODS: The study partnered with Kenya’s Ministry of Health (MOH) and other organizations on community sensitization and engagement to mobilize, train and deploy community health volunteers (CHVs) to deliver MTaT in the community. Within the health facilities, the study availed staff, medical and laboratory supplies and strengthened health information management system to monitor progress and evaluate impact of intervention. RESULTS: More than 80 Kenya MOH CHVs, 13 clinical officers, field workers, data and logistical staff were trained to carry out MTaT three times a year for 2 years in a population of approximately 90,000 individuals. A supply chain management was adapted to meet daily demands for large volumes of commodities despite the limitation of few MOH facilities having ideal storage conditions. Modern technology was adapted more to meet the needs of the high daily volume of collected data. CONCLUSIONS: In resource-constrained settings, large interventions require capacity building and logistical planning. This study found that investing in relationships with the communities, local governments, and other partners, and identifying and equipping the appropriate staff with the skills and technology to perform tasks are important factors for success in delivering an intervention like MTaT. |
format | Online Article Text |
id | pubmed-6664589 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-66645892019-08-05 Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned Odero, Norbert Awino Samuels, Aaron M. Odongo, Wycliffe Abong’o, Bernard Gimnig, John Otieno, Kephas Odero, Christopher Obor, David Ombok, Maurice Were, Vincent Sang, Tony Hamel, Mary J. Kachur, S. Patrick Slutsker, Laurence Lindblade, Kim A. Kariuki, Simon Desai, Meghna Malar J Research BACKGROUND: Malaria transmission is high in western Kenya and the asymptomatic infected population plays a significant role in driving the transmission. Mathematical modelling and simulation programs suggest that interventions targeting asymptomatic infections through mass testing and treatment (MTaT) or mass drug administration (MDA) have the potential to reduce malaria transmission when combined with existing interventions. OBJECTIVE: This paper describes the study site, capacity development efforts required, and lessons learned for implementing a multi-year community-based cluster-randomized controlled trial to evaluate the impact of MTaT for malaria transmission reduction in an area of high transmission in western Kenya. METHODS: The study partnered with Kenya’s Ministry of Health (MOH) and other organizations on community sensitization and engagement to mobilize, train and deploy community health volunteers (CHVs) to deliver MTaT in the community. Within the health facilities, the study availed staff, medical and laboratory supplies and strengthened health information management system to monitor progress and evaluate impact of intervention. RESULTS: More than 80 Kenya MOH CHVs, 13 clinical officers, field workers, data and logistical staff were trained to carry out MTaT three times a year for 2 years in a population of approximately 90,000 individuals. A supply chain management was adapted to meet daily demands for large volumes of commodities despite the limitation of few MOH facilities having ideal storage conditions. Modern technology was adapted more to meet the needs of the high daily volume of collected data. CONCLUSIONS: In resource-constrained settings, large interventions require capacity building and logistical planning. This study found that investing in relationships with the communities, local governments, and other partners, and identifying and equipping the appropriate staff with the skills and technology to perform tasks are important factors for success in delivering an intervention like MTaT. BioMed Central 2019-07-29 /pmc/articles/PMC6664589/ /pubmed/31357997 http://dx.doi.org/10.1186/s12936-019-2896-6 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Odero, Norbert Awino Samuels, Aaron M. Odongo, Wycliffe Abong’o, Bernard Gimnig, John Otieno, Kephas Odero, Christopher Obor, David Ombok, Maurice Were, Vincent Sang, Tony Hamel, Mary J. Kachur, S. Patrick Slutsker, Laurence Lindblade, Kim A. Kariuki, Simon Desai, Meghna Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title | Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title_full | Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title_fullStr | Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title_full_unstemmed | Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title_short | Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned |
title_sort | community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western kenya: development of study site infrastructure and lessons learned |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664589/ https://www.ncbi.nlm.nih.gov/pubmed/31357997 http://dx.doi.org/10.1186/s12936-019-2896-6 |
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