Cargando…

Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes

OBJECTIVE: The aim of this study was to clarify the association of two single-nucleotide polymorphisms (SNPs) (rs11651270 and rs2670660) in the NLRP1 (NLR family pyrin domain containing 1) gene with type 1 diabetes (T1D) in the Chinese Han population. We hypothesize that mutations in the NLRP1 gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Xiaoxiao, Xia, Ying, Liu, Yue, Wang, Yanfei, Luo, Shuoming, Lin, Jian, Huang, Gan, Li, Xia, Xie, Zhiguo, Zhou, Zhiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664699/ https://www.ncbi.nlm.nih.gov/pubmed/31396539 http://dx.doi.org/10.1155/2019/7405120

Ejemplares similares

rs3806265 and rs4612666 of the NLRP3 Gene Are Associated With the Titer of Glutamic Acid Decarboxylase Antibody in Type 1 Diabetes
por: Sun, Xiaoxiao, et al.
Publicado: (2022)

Polymorphisms of the NLRC4 Gene are Associated with the Onset Age, Positive Rate of GADA and 2-h Postprandial C-Peptide in Patients with Type 1 Diabetes
por: Xu, Linling, et al.
Publicado: (2020)

The NLRP3 Inflammasome and Its Role in T1DM
por: Sun, Xiaoxiao, et al.
Publicado: (2020)

The polymorphism of the CARD8 inflammasome-related gene is associated with glutamic-acid-decarboxylase-antibody positivity in patients with type 1 diabetes mellitus
por: Pang, Haipeng, et al.
Publicado: (2021)

The missing heritability in type 1 diabetes
por: Pang, Haipeng, et al.
Publicado: (2022)

The Positivity Rate of IA-2A and ZnT8A in the Chinese Han Population With Type 1 Diabetes Mellitus: Association With rs1143627 and rs1143643 Polymorphisms in the IL1B Gene
por: Li, Jiaqi, et al.
Publicado: (2021)

Emerging roles of rare and low-frequency genetic variants in type 1 diabetes mellitus
por: Pang, Haipeng, et al.
Publicado: (2021)

Association analysis between the TLR9 gene polymorphism rs352140 and type 1 diabetes
por: Wang, Yimeng, et al.
Publicado: (2023)

Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM
por: Pang, Haipeng, et al.
Publicado: (2020)

The m6A methylation profiles of immune cells in type 1 diabetes mellitus
por: Wang, Yimeng, et al.
Publicado: (2022)

Emerging Roles of Exosomes in T1DM
por: Pang, Haipeng, et al.
Publicado: (2020)

Characterization of lncRNA Profiles of Plasma-Derived Exosomes From Type 1 Diabetes Mellitus
por: Pang, Haipeng, et al.
Publicado: (2022)

Differential Expression and Bioinformatics Analysis of Plasma-Derived Exosomal circRNA in Type 1 Diabetes Mellitus
por: Pang, Haipeng, et al.
Publicado: (2022)

Identification of hsa_circRNA_100632 as a novel molecular biomarker for fulminant type 1 diabetes
por: Yin, Wenfeng, et al.
Publicado: (2023)

New Developments in T Cell Immunometabolism and Therapeutic Implications for Type 1 Diabetes
por: Zhang, Mengdi, et al.
Publicado: (2022)

Plasma-derived exosomal mRNA profiles associated with type 1 diabetes mellitus
por: Fan, Wenqi, et al.
Publicado: (2022)

Association of the rs1990760, rs3747517, and rs10930046 polymorphisms in the IFIH1 gene with susceptibility to autoimmune diseases: a meta-analysis
por: Xiao, Zilin, et al.
Publicado: (2023)

Exploration of Users’ Perspectives and Needs and Design of a Type 1 Diabetes Management Mobile App: Mixed-Methods Study
por: Zhang, Yiyu, et al.
Publicado: (2018)

Characterization of immune checkpoint inhibitor-associated fulminant type 1 diabetes associated with autoantibody status and ethnic origin
por: Qiu, Junlin, et al.
Publicado: (2022)

Effectiveness of Lilly Connected Care Program (LCCP) App-Based Diabetes Education for Patients With Type 2 Diabetes Treated With Insulin: Retrospective Real-World Study
por: Zhang, Yiyu, et al.
Publicado: (2020)

Protein ubiquitination in T cell development
por: Zhong, Ting, et al.
Publicado: (2022)

Circular RNAs in diabetes and its complications: Current knowledge and future prospects
por: Yin, Wenfeng, et al.
Publicado: (2022)

Analysis of potential hub genes involved in the pathogenesis of Chinese type 1 diabetic patients
por: Yang, Shuting, et al.
Publicado: (2020)

Use, Perspectives, and Attitudes Regarding Diabetes Management Mobile Apps Among Diabetes Patients and Diabetologists in China: National Web-Based Survey
por: Zhang, Yiyu, et al.
Publicado: (2019)

Factors Influencing Patients’ Intentions to Use Diabetes Management Apps Based on an Extended Unified Theory of Acceptance and Use of Technology Model: Web-Based Survey
por: Zhang, Yiyu, et al.
Publicado: (2019)

Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes
por: Wang, Yanfei, et al.
Publicado: (2018)

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model
por: Luo, Beibei, et al.
Publicado: (2014)

Effectiveness of the Family Portal Function on the Lilly Connected Care Program (LCCP) for Patients With Type 2 Diabetes: Retrospective Cohort Study With Propensity Score Matching
por: Zhang, Yiyu, et al.
Publicado: (2021)

Latent autoimmune diabetes in adults in China
por: Qiu, Junlin, et al.
Publicado: (2022)

Role of Tet2 in Regulating Adaptive and Innate Immunity
por: Li, Jiaqi, et al.
Publicado: (2021)

A clinical diagnostic model based on an eXtreme Gradient Boosting algorithm to distinguish type 1 diabetes
por: Tang, Xiaohan, et al.
Publicado: (2021)

Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus
por: Yi, Bo, et al.
Publicado: (2016)

Prevalence of maturity-onset diabetes of the young in phenotypic type 2 diabetes in young adults: a nationwide, multi-center, cross-sectional survey in China
por: Chen, Yan, et al.
Publicado: (2023)

Structured nutrition and advanced carbohydrate counting questionnaire for adult type 1 diabetes
por: Huang, Fansu, et al.
Publicado: (2023)

Latent autoimmune diabetes in adults: a focus on β-cell protection and therapy
por: Yin, Wenfeng, et al.
Publicado: (2022)

Fulminant type 1 diabetes after COVID-19 vaccination
por: Tang, Xiaohan, et al.
Publicado: (2022)

Distribution of autoantibodies to insulinoma‐associated antigen‐2 and zinc transporter 8 in type 1 diabetes and latent autoimmune diabetes: A nationwide, multicentre, cross‐sectional study
por: Fan, Wenqi, et al.
Publicado: (2022)

Identification of Sorafenib as a Treatment for Type 1 Diabetes
por: Zeng, Qin, et al.
Publicado: (2022)

Circular RNAs in diabetes mellitus and its complications
por: Fan, Wenqi, et al.
Publicado: (2022)

Establishment of a type 1 diabetes structured education programme suitable for Chinese patients: type 1 diabetes education in lifestyle and self adjustment (TELSA)
por: Xie, Yuting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pj5n5mjjld169gj1ntd0ju8heo