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CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers

BACKGROUND: Multiple factors, including co-exposure between lifestyle and environmental risks, are important in susceptibility to oxidative DNA damage. However, the underlying mechanism is not fully understood. This study was undertaken to evaluate whether Cytochrome P4501A1 (CYP1A1) methylation can...

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Detalles Bibliográficos
Autores principales: Liu, Yanli, Li, Xuejing, Zhang, Bin, Fu, Ye, Yang, Aimin, Zhang, Hongjie, Zhang, Huitao, Niu, Yingying, Nie, Jisheng, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664755/
https://www.ncbi.nlm.nih.gov/pubmed/31358014
http://dx.doi.org/10.1186/s12940-019-0508-0