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A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington’s disease patients

Huntington’s disease (HD) is a progressive neurodegenerative disease. Involuntary movements, cognitive impairment and psychiatric disturbance are the major clinical manifestations, and gradual atrophy and selective neuronal loss in the striatum and cerebral cortex are the pathologic hallmarks. HD is...

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Detalles Bibliográficos
Autores principales:	Liu, Peng, Smith, Benjamin R., Huang, Eric S., Mahesh, Abhishek, Vonsattel, Jean Paul G., Petersen, Ashley J., Gomez-Pastor, Rocio, Ashe, Karen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664763/ https://www.ncbi.nlm.nih.gov/pubmed/31358058 http://dx.doi.org/10.1186/s40478-019-0764-9

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