Novel natural and synthetic inhibitors of solute carriers SGLT1 and SGLT2

Selective analogs of the natural glycoside phloridzin are marketed drugs that reduce hyperglycemia in diabetes by inhibiting the active sodium glucose cotransporter SGLT2 in the kidneys. In addition, intestinal SGLT1 is now recognized as a target for glycemic control. To expand available type 2 diab...

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Detalles Bibliográficos
Autores principales: Oranje, Paul, Gouka, Robin, Burggraaff, Lindsey, Vermeer, Mario, Chalet, Clément, Duchateau, Guus, van der Pijl, Pieter, Geldof, Marian, de Roo, Niels, Clauwaert, Fenja, Vanpaeschen, Toon, Nicolaï, Johan, de Bruyn, Tom, Annaert, Pieter, IJzerman, Adriaan P., van Westen, Gerard J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664820/
https://www.ncbi.nlm.nih.gov/pubmed/31384471
http://dx.doi.org/10.1002/prp2.504

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