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BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation

BACKGROUND: Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell line...

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Detalles Bibliográficos
Autores principales:	Bezerra, Patrícia Heloise Alves, Ferreira, Isadora Marques, Franceschi, Beatriz Tinoco, Bianchini, Francine, Ambrósio, Luciana, Cintra, Adélia Cristina O., Sampaio, Suely Vilela, de Castro, Fabíola Attié, Torqueti, Maria Regina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Centro de Estudos de Venenos e Animais Peçonhentos 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665320/ https://www.ncbi.nlm.nih.gov/pubmed/31384244 http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0010

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