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Attainment of target rifampicin concentrations in cerebrospinal fluid during treatment of tuberculous meningitis

OBJECTIVE: There is considerable uncertainty regarding the optimal use of rifampicin for the treatment of tuberculous (TB) meningitis. A pharmacokinetic modeling and simulation study of rifampicin concentrations in cerebrospinal fluid (CSF) during TB meningitis treatment was performed in this study....

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Detalles Bibliográficos
Autores principales:	Mezochow, Alyssa, Thakur, Kiran T., Zentner, Isaac, Subbian, Selvakumar, Kagan, Leonid, Vinnard, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666413/ https://www.ncbi.nlm.nih.gov/pubmed/31051278 http://dx.doi.org/10.1016/j.ijid.2019.04.026

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