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Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory

[Image: see text] Annotation and identification of metabolite biomarkers is critical for their biological interpretation in metabolic phenotyping studies, presenting a significant bottleneck in the successful implementation of untargeted metabolomics. Here, a systematic multistep protocol was develo...

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Detalles Bibliográficos
Autores principales: Whiley, Luke, Chekmeneva, Elena, Berry, David J, Jiménez, Beatriz, Yuen, Ada H. Y., Salam, Ash, Hussain, Humma, Witt, Matthias, Takats, Zoltan, Nicholson, Jeremy, Lewis, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666900/
https://www.ncbi.nlm.nih.gov/pubmed/31188566
http://dx.doi.org/10.1021/acs.analchem.9b00241