Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway

Metastasis is the major cause of cancer-related morbidity and mortality. The ability of cancer cells to become invasive and migratory contribute significantly to metastatic growth, which necessitates the identification of novel anti-migratory and anti-invasive therapeutic approaches. Proteoglycan 4...

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Detalles Bibliográficos
Autores principales: Sarkar, Anusi, Chanda, Ayan, Regmi, Suresh C., Karve, Kunal, Deng, Lili, Jay, Gregory D., Jirik, Frank R., Schmidt, Tannin A., Bonni, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667139/
https://www.ncbi.nlm.nih.gov/pubmed/31361756
http://dx.doi.org/10.1371/journal.pone.0219697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667139/
https://www.ncbi.nlm.nih.gov/pubmed/31361756
http://dx.doi.org/10.1371/journal.pone.0219697

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