The interaction between RE1-silencing transcription factor (REST) and heat shock protein 90 as new therapeutic target against Huntington’s disease

The wild type huntingtin protein (Htt), supports the production of brain-derived neurotrophic factor (BDNF), a survival factor for striatal neurons, through cytoplasmic sequestering of RE-1silencing transcription factor (REST). In Huntington´s Disease an inherited degenerative disease, caused by a C...

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Detalles Bibliográficos
Autores principales: Orozco-Díaz, Raúl, Sánchez-Álvarez, Angélica, Hernández-Hernández, José Manuel, Tapia-Ramírez, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667143/
https://www.ncbi.nlm.nih.gov/pubmed/31361762
http://dx.doi.org/10.1371/journal.pone.0220393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667143/
https://www.ncbi.nlm.nih.gov/pubmed/31361762
http://dx.doi.org/10.1371/journal.pone.0220393

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