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The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Antimicrobial peptides (AMPs) are small cationic molecules best known as mediators of the innate defence against microbial infection. While in vitro and ex vivo evidence suggest AMPs’ capacity to kill cancer cells, in vivo demonstration of an anti-tumour role of endogenous AMPs is lacking. Using a D...

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Detalles Bibliográficos
Autores principales: Parvy, Jean-Philippe, Yu, Yachuan, Dostalova, Anna, Kondo, Shu, Kurjan, Alina, Bulet, Philippe, Lemaître, Bruno, Vidal, Marcos, Cordero, Julia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667213/
https://www.ncbi.nlm.nih.gov/pubmed/31358113
http://dx.doi.org/10.7554/eLife.45061