ER stress abrogates the immunosuppressive effect of IL-10 on human macrophages through inhibition of STAT3 activation

OBJECTIVE AND DESIGN: To determine whether ER stress affects the inhibitory pathways of the human immune system, particularly the immunosuppressive effect of IL-10 on macrophages. MATERIAL OR SUBJECTS: In vitro stimulation of human monocyte-derived macrophages. TREATMENT: Cells were stimulated with...

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Detalles Bibliográficos
Autores principales: Hansen, Ivo S., Schoonejans, Josca M., Sritharan, Lathees, van Burgsteden, Johan A., Ambarus, Carmen A., Baeten, Dominique L. P., den Dunnen, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667425/
https://www.ncbi.nlm.nih.gov/pubmed/31227842
http://dx.doi.org/10.1007/s00011-019-01261-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667425/
https://www.ncbi.nlm.nih.gov/pubmed/31227842
http://dx.doi.org/10.1007/s00011-019-01261-9

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