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Genetic basis of functional variability in adhesion G protein-coupled receptors

The enormous sizes of adhesion G protein-coupled receptors (aGPCRs) go along with complex genomic exon-intron architectures giving rise to multiple mRNA variants. There is a need for a comprehensive catalog of aGPCR variants for proper evaluation of the complex functions of aGPCRs found in structura...

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Detalles Bibliográficos
Autores principales: Knierim, Alexander Bernd, Röthe, Juliane, Çakir, Mehmet Volkan, Lede, Vera, Wilde, Caroline, Liebscher, Ines, Thor, Doreen, Schöneberg, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667449/
https://www.ncbi.nlm.nih.gov/pubmed/31363148
http://dx.doi.org/10.1038/s41598-019-46265-x