Cargando…

m(6)A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis

Despite the vast number of modification sites mapped within mRNAs, known examples of consequential mRNA modifications remain rare. Here, we provide multiple lines of evidence to show that Ime4p, an N6-methyladenosine (m(6)A) methyltransferase required for meiosis in yeast, acts by methylating a site...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bushkin, G. Guy, Pincus, David, Morgan, Jeffrey T., Richardson, Kris, Lewis, Caroline, Chan, Sze Ham, Bartel, David P., Fink, Gerald R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667471/ https://www.ncbi.nlm.nih.gov/pubmed/31363087 http://dx.doi.org/10.1038/s41467-019-11232-7

Ejemplares similares

Effectiveness of reverse twin block with lip pads-RME and face mask with RME in the early treatment of class III malocclusion
por: Minase, Rohit A., et al.
Publicado: (2019)

Rapid Maxillary Expansion (RME): An Otolaryngologic Perspective
por: Cerritelli, Luca, et al.
Publicado: (2022)

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening
por: Beaudoin, Jean-Denis, et al.
Publicado: (2013)

3′ UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts
por: Spies, Noah, et al.
Publicado: (2013)

CRISPR-Mediated Knockout of Long 3′ UTR mRNA Isoforms in mESC-Derived Neurons
por: Bae, Bongmin, et al.
Publicado: (2021)

A position-specific 3′UTR sequence that accelerates mRNA decay
por: Geissler, Rene, et al.
Publicado: (2016)

Dynamic Variations of 3′UTR Length Reprogram the mRNA Regulatory Landscape
por: Navarro, Estanislao, et al.
Publicado: (2021)

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
por: Liu, Wenbo, et al.
Publicado: (2017)

New mRNA modification?
por: Leslie, Mitch
Publicado: (2007)

External root resorption (ERR) and rapid maxillary expansion (RME) at post-retention stage: a comparison between tooth-borne and bone-borne RME
por: Leonardi, Rosalia, et al.
Publicado: (2022)

Kar4, the Yeast Homolog of METTL14, is Required for mRNA m(6)A Methylation and Meiosis
por: Park, Zachory M., et al.
Publicado: (2023)

Vir1p, the Yeast Homolog of Virilizer, is Required for mRNA m(6)A Methylation and Meiosis
por: Park, Zachory M., et al.
Publicado: (2023)

Kar4, the yeast homolog of METTL14, is required for mRNA m(6)A methylation and meiosis
por: Park, Zachory M., et al.
Publicado: (2023)

miR-526b targets 3′ UTR of MMP1 mRNA
por: Kim, Kyu-Han, et al.
Publicado: (2015)

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses
por: Bauer, Karl E., et al.
Publicado: (2019)

3′UTRs Regulate Mouse Ntrk2 mRNA Distribution in Cortical Neurons
por: Chen, Shangqin, et al.
Publicado: (2020)

Identification of 3′ UTR motifs required for mRNA localization to myelin sheaths in vivo
por: Yergert, Katie M., et al.
Publicado: (2021)

Staufen1-mediated mRNA decay induces Requiem mRNA decay through binding of Staufen1 to the Requiem 3′UTR
por: Kim, Min Young, et al.
Publicado: (2014)

Long 3′-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae
por: Kebaara, Bessie W., et al.
Publicado: (2009)

mRNA modifications: Dynamic regulators of gene expression?
por: Hoernes, Thomas Philipp, et al.
Publicado: (2016)

Post-transcriptional repression of mRNA enhances competence to transit from mitosis to meiosis in mouse spermatogenic cells
por: Mikedis, Maria M., et al.
Publicado: (2023)

CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay
por: Masuda, Akio, et al.
Publicado: (2012)

Regulation of thrombospondin-1 expression through AU-rich elements in the 3′UTR of the mRNA
por: Mcgray, Asa J. Robert, et al.
Publicado: (2010)

A combinatorial code for mRNA 3′-UTR-mediated translational control in the mouse oocyte
por: Dai, Xing-Xing, et al.
Publicado: (2019)

AR mRNA stability is increased with AR-antagonist resistance via 3′UTR variants
por: Dart, D A, et al.
Publicado: (2019)

Structural recognition of the mRNA 3′ UTR by PUF-8 restricts the lifespan of C. elegans
por: Xu, Zheng, et al.
Publicado: (2021)

ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes
por: Rothamel, Katherine, et al.
Publicado: (2021)

Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA
por: Grayeski, Philip J, et al.
Publicado: (2022)

JUN mRNA Translation Regulation is Mediated by Multiple 5’ UTR and Start Codon Features
por: González-Sánchez, Angélica M., et al.
Publicado: (2023)

Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling
por: Gomez-Lamarca, Maria, et al.
Publicado: (2015)

Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling
por: Gomez-Lamarca, Maria J., et al.
Publicado: (2015)

Effect of 3′UTR RET Variants on RET mRNA Secondary Structure and Disease Presentation in Medullary Thyroid Carcinoma
por: Ceolin, Lucieli, et al.
Publicado: (2016)

Analysis of mRNA m(6)A modification and mRNA expression profiles in middle ear cholesteatoma
por: Xie, Shumin, et al.
Publicado: (2023)

Massively parallel analysis of human 3′ UTRs reveals that AU-rich element length and registration predict mRNA destabilization
por: Siegel, David A, et al.
Publicado: (2021)

In search of the mRNA modification landscape in plants
por: Chmielowska-Bąk, Jagna, et al.
Publicado: (2019)

RNA modification in mRNA cancer vaccines
por: Mei, Yingxue, et al.
Publicado: (2023)

Modifications of mRNA vaccine structural elements for improving mRNA stability and translation efficiency
por: Kim, Sun Chang, et al.
Publicado: (2021)

ElrA binding to the 3′UTR of cyclin E1 mRNA requires polyadenylation elements
por: Slevin, Michael K., et al.
Publicado: (2007)

β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3′-UTR
por: Lee, Hee Kyu, et al.
Publicado: (2006)

Evidence that the Upf1-related molecular motor scans the 3′-UTR to ensure mRNA integrity
por: Shigeoka, Toshiaki, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_26so09e9u3a3ekudpg3168f6d0