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Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons
OBJECTIVE: Reelin (RELN) is a large glycoprotein involved in synapse maturation and neuronal organization throughout development. Deficits in RELN signaling contribute to multiple psychological disorders, such as autism spectrum disorder, schizophrenia, and bipolar disorder. Nutritional stress alter...
Autores principales: | Roberts, Brandon L., Bennett, Baylin J., Bennett, Camdin M., Carroll, Julie M., Dalbøge, Louise S., Hall, Colin, Hassouneh, Wafa, Heppner, Kristy M., Kirigiti, Melissa A., Lindsley, Sarah R., Tennant, Katherine G., True, Cadence A., Whittle, Andrew, Wolf, Anitra C., Roberts, Charles T., Tang-Christensen, Mads, Sleeman, Mark W., Cowley, Michael A., Grove, Kevin L., Kievit, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667498/ https://www.ncbi.nlm.nih.gov/pubmed/31230943 http://dx.doi.org/10.1016/j.molmet.2019.06.001 |
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