Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy

Despite the administration of multiple drugs that are highly effective in vitro, tuberculosis (TB) treatment requires prolonged drug administration and is confounded by the emergence of drug-resistant strains. To understand the mechanisms that limit antibiotic efficacy, we performed a comprehensive...

Descripción completa

Detalles Bibliográficos
Autores principales: Bellerose, Michelle M., Baek, Seung-Hun, Huang, Chuan-Chin, Moss, Caitlin E., Koh, Eun-Ik, Proulx, Megan K., Smith, Clare M., Baker, Richard E., Lee, Jong Seok, Eum, Seokyong, Shin, Sung Jae, Cho, Sang-Nae, Murray, Megan, Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667613/
https://www.ncbi.nlm.nih.gov/pubmed/31363023
http://dx.doi.org/10.1128/mBio.00663-19

Ejemplares similares

Ejemplares similares