Endogenous Retrovirus-Derived Long Noncoding RNA Enhances Innate Immune Responses via Derepressing RELA Expression

Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles in disease such as tumorigenesis. Recent advances also suggest that this “enemy within” may encode a viral mimic to induce antiviral immune responses through viral sensors....

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Detalles Bibliográficos
Autores principales: Zhou, Bin, Qi, Fei, Wu, Fangyi, Nie, Hongbo, Song, Yifan, Shao, Lu, Han, Jingxuan, Wu, Zhen, Saiyin, Hexige, Wei, Gang, Wang, Penghua, Ni, Ting, Qian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667616/
https://www.ncbi.nlm.nih.gov/pubmed/31363026
http://dx.doi.org/10.1128/mBio.00937-19

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