Cargando…

Novel purine thioglycoside analogs: synthesis, nanoformulation and biological evaluation in in vitro human liver and breast cancer models

Background: A series of novel pyrazolopyrimidine and pyrazololpyridine thioglycosides were synthesized and confirmed via their spectral analyses. Purpose: To evaluate the effect of these anti-metabolic compounds against proliferation of Huh-7 and Mcf-7 as in vitro models of human liver and breast can...

Descripción completa

Detalles Bibliográficos
Autores principales: Abu-Zaied, Mamdouh A, Loutfy, Samah A, Hassan, Ashraf E, Elgemeie, Galal H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667681/
https://www.ncbi.nlm.nih.gov/pubmed/31440030
http://dx.doi.org/10.2147/DDDT.S201249