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Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus

OBJECTIVE: The liver regulates the availability of insulin to other tissues and is the first line insulin response organ physiologically exposed to higher insulin concentrations than the periphery. Basal insulin during fasting inhibits hepatic gluconeogenesis and glycogenolysis, whereas postprandial...

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Detalles Bibliográficos
Autores principales:	Backman, Mattias, Flenkenthaler, Florian, Blutke, Andreas, Dahlhoff, Maik, Ländström, Erik, Renner, Simone, Philippou-Massier, Julia, Krebs, Stefan, Rathkolb, Birgit, Prehn, Cornelia, Grzybek, Michal, Coskun, Ünal, Rothe, Michael, Adamski, Jerzy, de Angelis, Martin Hrabĕ, Wanke, Rüdiger, Fröhlich, Thomas, Arnold, Georg J., Blum, Helmut, Wolf, Eckhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667734/ https://www.ncbi.nlm.nih.gov/pubmed/31221621 http://dx.doi.org/10.1016/j.molmet.2019.05.011

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