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AML-derived mesenchymal stem cells upregulate CTGF expression through the BMP pathway and induce K562-ADM fusiform transformation and chemoresistance

Bone marrow-derived mesenchymal stem cells (MSCs), are the basic cellular components that make up the bone marrow microenvironment (BMM). In acute myeloid leukemia (AML), the morphology and function of MSCs changes in accordance with the transformation of the BMM. Moreover, the transformation of MSC...

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Detalles Bibliográficos
Autores principales: Li, Haiying, Li, Juan, Cheng, Juan, Chen, Xuan, Zhou, Lanxia, Li, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667869/
https://www.ncbi.nlm.nih.gov/pubmed/31322275
http://dx.doi.org/10.3892/or.2019.7237

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