Cargando…
Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancer
The antipsychotic drug pimozide has been found to exhibit anticancer effects. Previously, it was demonstrated that pimozide inhibits hepatocellular carcinoma (HCC) cell growth, but its pharmacodynamic characteristics remain unclear. The aim of the present study was to investigate the reversibility a...
Autores principales: | Chen, Jia-Jie, Zhang, Li-Na, Cai, Nan, Zhang, Zhen, Ji, Kunmei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667923/ https://www.ncbi.nlm.nih.gov/pubmed/31322218 http://dx.doi.org/10.3892/or.2019.7229 |
Ejemplares similares
-
Inhibition of wnt/β-catenin Signaling in Hepatocellular Carcinoma by an Antipsychotic Drug Pimozide
por: Fako, Valerie, et al.
Publicado: (2016) -
The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma
por: Chen, Jia-Jie, et al.
Publicado: (2015) -
Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy
por: Ranjan, Alok, et al.
Publicado: (2020) -
Pimozide: An Old Wine in a New Bottle!
por: Naguy, Ahmed
Publicado: (2017) -
Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae
por: Kalamarz, Marta E., et al.
Publicado: (2011)