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The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia
Recent studies suggest that mild hypoxia-induced neonatal seizures can trigger an acute neuroinflammatory response leading to long-lasting changes in brain excitability along with associated cognitive and behavioral deficits. The cellular elements and signaling pathways underlying neuroinflammation...
Autores principales: | Quinlan, Sean, Merino-Serrais, Paula, Di Grande, Alessandra, Dussmann, Heiko, Prehn, Jochen H. M., Ní Chonghaile, Tríona, Henshall, David C., Jimenez-Mateos, Eva M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667988/ https://www.ncbi.nlm.nih.gov/pubmed/31396238 http://dx.doi.org/10.3389/fimmu.2019.01752 |
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