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Silibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity

PURPOSE: Ovarian cancer is the most lethal cancer among all gynaecological malignancies. The combination theraputics of cisplatin and taxol is widely used in clinicals for ovarian cancer treatment. However, long-term use of cisplatin and taxol induces strong tolerance and hepatotoxicity. Since silib...

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Detalles Bibliográficos
Autores principales:	Yang, Zhichun, Pan, Qionghui, Zhang, Dingfang, Chen, Jianqiang, Qiu, Yinda, Chen, Xiaojing, Zheng, Feiyun, Lin, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668021/ https://www.ncbi.nlm.nih.gov/pubmed/31440098 http://dx.doi.org/10.2147/CMAR.S201341

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