Cargando…

The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21

Melanoma is the deadliest form of skin cancer, affecting men more frequently and severely than women. Although recent studies suggest that differences in activity of the androgen receptor (AR) underlie the observed sex bias, little is known about AR activity in melanoma. Here we show that AR and EGR...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Karyn, Carroll, Johanna S., Yee, Elaine, Thomas, Dolly D., Wert-Lamas, Leon, Neier, Steven C., Sheynkman, Gloria, Ritz, Justin, Novina, Carl D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668037/
https://www.ncbi.nlm.nih.gov/pubmed/31116991
http://dx.doi.org/10.1016/j.celrep.2019.04.101