Neutrophil elastase as a biomarker for bacterial infection in COPD

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is predominantly associated with neutrophilic inflammation. Active neutrophil elastase (NE) is a serine proteinase, secreted by neutrophils, in response to inflammation and pathogen invasion. We sought to investigate if NE could be used as a b...

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Detalles Bibliográficos
Autores principales: Thulborn, Samantha J., Mistry, Vijay, Brightling, Christopher E., Moffitt, Kelly L., Ribeiro, David, Bafadhel, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668103/
https://www.ncbi.nlm.nih.gov/pubmed/31362723
http://dx.doi.org/10.1186/s12931-019-1145-4

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