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Functional consequences of enhanced expression of STIM1 and Orai1 in Huh-7 hepatocellular carcinoma tumor-initiating cells

BACKGROUND: The endoplasmic reticulum (ER) Ca(2+) sensor, stromal interaction molecule1 (STIM1) activates the plasma membrane (PM) channel Orai1 in order to mediate store-operated Ca(2+) entry (SOCE) in response to ER store depletion. Enhanced expression of STIM1 in cancer tissue has been associated...

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Detalles Bibliográficos
Autores principales:	Karacicek, B., Erac, Y., Tosun, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668110/ https://www.ncbi.nlm.nih.gov/pubmed/31366337 http://dx.doi.org/10.1186/s12885-019-5947-z

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