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A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

Lewy body diseases are neurodegenerative disorders characterized by Lewy bodies in the brain. Lewy body dementia (LBD) refers to two forms of Lewy body disease: Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB). Tau is a cytoskeletal protein found in neurofibrillary tangles...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin R., Nelson, Kathryn M., Kemper, Lisa J., Leinonen-Wright, Kailee, Petersen, Ashley, Keene, C. Dirk, Ashe, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668119/
https://www.ncbi.nlm.nih.gov/pubmed/31362787
http://dx.doi.org/10.1186/s40478-019-0765-8