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A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease
Lewy body diseases are neurodegenerative disorders characterized by Lewy bodies in the brain. Lewy body dementia (LBD) refers to two forms of Lewy body disease: Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB). Tau is a cytoskeletal protein found in neurofibrillary tangles...
Autores principales: | Smith, Benjamin R., Nelson, Kathryn M., Kemper, Lisa J., Leinonen-Wright, Kailee, Petersen, Ashley, Keene, C. Dirk, Ashe, Karen H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668119/ https://www.ncbi.nlm.nih.gov/pubmed/31362787 http://dx.doi.org/10.1186/s40478-019-0765-8 |
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