Assessment of dapagliflozin effect on diabetic endothelial dysfunction of brachial artery (ADDENDA-BHS2 trial): rationale, design, and baseline characteristics of a randomized controlled trial

BACKGROUND: Endothelial dysfunction (ED) is a hallmark in type 2 diabetes mellitus (T2DM) that favor both atherogenesis and ischemia and reperfusion injury (IRI). Sodium-glucose-2 co-transporter inhibitors (SGLT2i) may hypothetically improve microvascular and macrovascular functions via a broad spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Cintra, Riobaldo M. R., Soares, Alexandre A. S., Breder, Ikaro, Munhoz, Daniel B., Barreto, Joaquim, Kimura-Medorima, Sheila T., Cavalcante, Pamela, Zanchetta, Renata, Breder, Jessica Cunha, Moreira, Camila, Virginio, Vitor W., Bonilha, Isabella, Lima-Junior, Jose Carlos, Coelho-Filho, Otavio R., Wolf, Vaneza L. W., Guerra-Junior, Gil, Oliveira, Daniela C., Haeitmann, Rodrigo, Fernandes, Vicente H. R., Nadruz, Wilson, Chaves, Fernando R. P., Arieta, Carlos E. L., Quinaglia, Thiago, Sposito, Andrei C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668143/
https://www.ncbi.nlm.nih.gov/pubmed/31384310
http://dx.doi.org/10.1186/s13098-019-0457-3

Ejemplares similares

Ejemplares similares