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Cerebrospinal Fluid Markers of Synaptic Injury and Functional Connectivity in Alzheimer Disease: Protocol for a Cross-Sectional Study
BACKGROUND: Synaptic loss is the best surrogate for cognitive decline in Alzheimer disease (AD) and is more closely associated with cognitive function than amyloid or tau pathologies. Neurogranin (Ng) and synaptosome–associated protein-25 (SNAP-25) have demonstrated utility as cerebrospinal fluid (C...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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JMIR Publications
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668296/ https://www.ncbi.nlm.nih.gov/pubmed/31271547 http://dx.doi.org/10.2196/14302 |