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Maturation of coagulation factor IX during Xase formation as deduced using factor VIII‐derived peptides

Blood coagulation involves extrinsic and intrinsic pathways, which merge at the activation step of blood coagulation factor X to factor Xa. This step is catalysed by the extrinsic or intrinsic Xase, which consists of a complex of factor VIIa and its cofactor tissue factor or factor IXa (FIXa) and it...

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Detalles Bibliográficos
Autores principales: Fang, Han, Zögg, Thomas, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668378/
https://www.ncbi.nlm.nih.gov/pubmed/31077577
http://dx.doi.org/10.1002/2211-5463.12653