Cargando…
Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells
Ovarian cancer is an intra-abdominal tumor in which the presence of ascites facilitates metastatic dissemination, and associated with poor prognosis. However, the significance of metabolic alterations in ovarian cancer cells in the ascites microenvironment remains unclear. Here we show ovarian cance...
Autores principales: | Chen, Rain R., Yung, Mingo M. H., Xuan, Yang, Zhan, Shijie, Leung, Leanne L., Liang, Rachel R., Leung, Thomas H. Y., Yang, Huijuan, Xu, Dakang, Sharma, Rakesh, Chan, Karen K. L., Ngu, Siew-Fei, Ngan, Hextan Y. S., Chan, David W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668395/ https://www.ncbi.nlm.nih.gov/pubmed/31372520 http://dx.doi.org/10.1038/s42003-019-0508-1 |
Ejemplares similares
-
New Insights into Ferroptosis Initiating Therapies (FIT) by Targeting the Rewired Lipid Metabolism in Ovarian Cancer Peritoneal Metastases
por: Zhan, Shijie, et al.
Publicado: (2022) -
GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade
por: Yung, Mingo Ming-Ho, et al.
Publicado: (2018) -
Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways
por: Chen, Kangmei, et al.
Publicado: (2018) -
A patient with relapsed high-grade serous ovarian carcinoma with somatic RAD51C mutations treated with PARPi monotherapy: a case report
por: Ngu, Siew-Fei, et al.
Publicado: (2022) -
Orchestrated Action of AMPK Activation and Combined VEGF/PD-1 Blockade with Lipid Metabolic Tunning as Multi-Target Therapeutics against Ovarian Cancers
por: Yung, Mingo M. H., et al.
Publicado: (2022)