Cargando…

Quantitative analysis of nasal transcripts reveals potential biomarkers for Parkinson’s disease

Patients with Parkinson’s disease (PD) oftentimes develop olfactory dysfunction in their early stages, converting the nasal environment into a useful source of potential biomarkers. Here we determined the possible application of nasal fluid cells for PD biomarker identification. Thirty PD patients a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyojung, Kang, Seok-Jae, Jo, Young Mi, Kim, Min Song, Lee, Yunjong, Cho, Seok-Hyun, Kim, Hee-Tae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668404/ https://www.ncbi.nlm.nih.gov/pubmed/31366968 http://dx.doi.org/10.1038/s41598-019-47579-6

Ejemplares similares

Novel Nasal Epithelial Cell Markers of Parkinson’s Disease Identified Using Cells Treated with α-Synuclein Preformed Fibrils
por: Kim, Hyojung, et al.
Publicado: (2020)

Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson’s Disease via a Vitamin D Receptor-Dependent Pathway
por: Kim, Hyojung, et al.
Publicado: (2020)

Phosphoinositide 3-kinase-delta could be a biomarker for eosinophilic nasal polyps
por: Kim, Jong Seung, et al.
Publicado: (2018)

Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress
por: Kim, Hyojung, et al.
Publicado: (2019)

Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model
por: Ham, Sangwoo, et al.
Publicado: (2017)

The Effectiveness of Budesonide Nasal Irrigation After Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Asthma
por: Kang, Tae Wook, et al.
Publicado: (2017)

Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models
por: Ramalingam, Mahesh, et al.
Publicado: (2018)

Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson’s Disease
por: Ham, Sangwoo, et al.
Publicado: (2019)

Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models
por: Kim, Hyojung, et al.
Publicado: (2017)

The nasal symbiont Staphylococcus species restricts the transcription of SARS-CoV-2 entry factors in human nasal epithelium
por: Ji, Jeong-Yeon, et al.
Publicado: (2021)

Aggravation of Relapsing Polychondritis due to the Infection and Its Manifestation on a Nasal Tip Graft
por: Son, Seung Beom, et al.
Publicado: (2014)

Poly (ADP-ribose) in the pathogenesis of Parkinson's disease
por: Lee, Yunjong, et al.
Publicado: (2014)

Nasal and Exhaled Nitric Oxide in Allergic Rhinitis
por: Lee, Keon Jung, et al.
Publicado: (2012)

CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation
por: Kim, Hyojung, et al.
Publicado: (2017)

Amyloid beta in nasal secretions may be a potential biomarker of Alzheimer’s disease
por: Kim, Young Hyo, et al.
Publicado: (2019)

Quantitative Analysis in Cervical Spinal Cord Injury Patients Using Diffusion Tensor Imaging and Tractography
por: Park, Geun Seok, et al.
Publicado: (2022)

The Long-Term Effects of Budesonide Nasal Irrigation in Chronic Rhinosinusitis with Asthma
por: Jung, Seon Min, et al.
Publicado: (2022)

Nasal symbiont Staphylococcus epidermidis restricts the cellular entry of influenza virus into the nasal epithelium
por: Jo, Ara, et al.
Publicado: (2022)

Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates
por: Ham, Sangwoo, et al.
Publicado: (2019)

Comparison of Nasal Swabs, Nasopharyngeal Swabs, and Saliva Samples for the Detection of SARS-CoV-2 and other Respiratory Virus Infections
por: Jung, Eun Ju, et al.
Publicado: (2023)

A Retrospective Exploratory Analysis for Serum Extracellular Vesicles Reveals APRIL (TNFSF13), CXCL13, and VEGF-A as Prognostic Biomarkers for Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer
por: Jung, Hae Hyun, et al.
Publicado: (2023)

Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson’s Disease
por: Sim, Hyuna, et al.
Publicado: (2020)

Distal Cholangiocarcinoma with Gastric Metastasis Mimicking Early Gastric Cancer
por: Kim, Eun-Mi, et al.
Publicado: (2009)

Parkinson’s Disease Subtyping Using Clinical Features and Biomarkers: Literature Review and Preliminary Study of Subtype Clustering
por: Lee, Seung Hyun, et al.
Publicado: (2022)

Potential association between coronary artery disease and the inflammatory biomarker YKL-40 in asymptomatic patients with type 2 diabetes mellitus
por: Kim, Hyun Min, et al.
Publicado: (2012)

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
por: Yun, Seung Pil, et al.
Publicado: (2018)

Healing of the nasal septal mucosa in an experimental rabbit model of mucosal injury
por: Choi, Kyu Young, et al.
Publicado: (2017)

Preoperative sterile pyuria as a prognostic biomarker for intravesical recurrence in upper urinary tract urothelial carcinoma
por: Jeon, Byeong Jo, et al.
Publicado: (2020)

Subtypes of Sleep Disturbance in Parkinson's Disease Based on the Cross-Culturally Validated Korean Version of Parkinson's Disease Sleep Scale-2
por: Yang, Hui-Jun, et al.
Publicado: (2020)

Upper eyelid reconstruction using a combination of a nasal septal chondromucosal graft and a Fricke flap: a case report
por: Lee, Ju Ho, et al.
Publicado: (2021)

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
por: Yun, Seung Pil, et al.
Publicado: (2017)

Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor
por: Lee, Hae-Ahm, et al.
Publicado: (2015)

Effect of expanding nanocellulose sponge on nasal mucosal defects in an animal model
por: Kim, Ji Won, et al.
Publicado: (2020)

Salivary Gland Uptake on (18)F-FP-CIT PET as a New Biomarker in Patients With Parkinsonism
por: Kang, Seo Young, et al.
Publicado: (2023)

Fabrication of Stacked MoS(2) Bilayer with Weak Interlayer Coupling by Reduced Graphene Oxide Spacer
por: Oh, Hye Min, et al.
Publicado: (2019)

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease
por: Karuppagounder, Senthilkumar S., et al.
Publicado: (2014)

Quantitative Analysis of SMN1 Gene and Estimation of SMN1 Deletion Carrier Frequency in Korean Population based on Real-Time PCR
por: Lee, Tae-Mi, et al.
Publicado: (2004)

Validation of the Korean Version of the Scale for Outcomes in Parkinson’s Disease-Autonomic
por: Kim, Ji-Young, et al.
Publicado: (2017)

Usefulness of indirect open reduction via a transconjunctival approach for the treatment of nasal bone fracture associated with orbital blowout fracture
por: Kim, Tae Ho, et al.
Publicado: (2018)

Erratum: Validation Study of the Official Korean Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale
por: Park, Jinse, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gukj2481lbqfsphmg0q0il5sn0