The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase

Nonribosomal peptide synthetases produce diverse natural products using a multidomain architecture where the growing peptide, attached to an integrated carrier domain, is delivered to neighboring catalytic domains for bond formation and modification. Investigation of these systems can lead to the di...

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Detalles Bibliográficos
Autores principales: Kreitler, Dale F., Gemmell, Erin M., Schaffer, Jason E., Wencewicz, Timothy A., Gulick, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668435/
https://www.ncbi.nlm.nih.gov/pubmed/31366889
http://dx.doi.org/10.1038/s41467-019-11383-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668435/
https://www.ncbi.nlm.nih.gov/pubmed/31366889
http://dx.doi.org/10.1038/s41467-019-11383-7

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