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Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells

Manganese (Mn) is an essential trace element, which also causes neurotoxicity in exposed occupational workers. Mn causes mitochondrial toxicity; however, little is known about transcriptional responses discriminated by physiological and toxicological levels of Mn. Identification of such mechanisms c...

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Detalles Bibliográficos
Autores principales: Fernandes, Jolyn, Chandler, Joshua D., Lili, Loukia N., Uppal, Karan, Hu, Xin, Hao, Li, Go, Young-Mi, Jones, Dean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668488/
https://www.ncbi.nlm.nih.gov/pubmed/31396262
http://dx.doi.org/10.3389/fgene.2019.00676