T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of (·)NO/cGMP Signaling

AIMS: The neutrophil recruiting cytokine Interleukin-17A (IL-17A) is a key component in vascular dysfunction and arterial hypertension. Moreover, IL-17A has a central role for the vascular infiltration of myeloid cells into the arterial wall in Angiotensin II-induced vascular inflammation. The inten...

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Detalles Bibliográficos
Autores principales: Schüler, Rebecca, Efentakis, Panagiotis, Wild, Johannes, Lagrange, Jérémy, Garlapati, Venkata, Molitor, Michael, Kossmann, Sabine, Oelze, Matthias, Stamm, Paul, Li, Huige, Schäfer, Katrin, Münzel, Thomas, Daiber, Andreas, Waisman, Ari, Wenzel, Philip, Karbach, Susanne Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668561/
https://www.ncbi.nlm.nih.gov/pubmed/31396305
http://dx.doi.org/10.1155/2019/6721531

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