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Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia

AIM: To estimate time to first optimal glycaemic control and identify prognostic factors among type 2 diabetes mellitus (T2DM) patients attending diabetes clinic of public teaching hospitals in Addis Ababa, Ethiopia. METHODS: A retrospective chart review study was conducted at diabetes clinic of Add...

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Autores principales: Leulseged, Tigist W., Ayele, Birhanu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668794/
https://www.ncbi.nlm.nih.gov/pubmed/31365544
http://dx.doi.org/10.1371/journal.pone.0220309
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author Leulseged, Tigist W.
Ayele, Birhanu T.
author_facet Leulseged, Tigist W.
Ayele, Birhanu T.
author_sort Leulseged, Tigist W.
collection PubMed
description AIM: To estimate time to first optimal glycaemic control and identify prognostic factors among type 2 diabetes mellitus (T2DM) patients attending diabetes clinic of public teaching hospitals in Addis Ababa, Ethiopia. METHODS: A retrospective chart review study was conducted at diabetes clinic of Addis Ababa’s public teaching hospitals among a randomly selected sample of 685 charts of patients with T2DMwho were on follow up from January 1, 2013 to June 30, 2017. Data was collected using data abstraction tool. Descriptive statistics, Kaplan Meier plots, median survival time, Log-rank test and Cox proportional hazard survival models were used for analysis. RESULTS: Median time to first optimal glycaemic control among the study population was 9.5 months. Factors that affect time to first optimal glycaemic control were age group (HR = 0.635, 95% CI: 0.486–0.831 for 50–59 years, HR = 0.558, 95% CI: 0.403–0.771for 60–69 years and HR = 0.495, 95% CI: 0.310–0.790 for > = 70 years), diabetes neuropathy (HR = 0.502, 95% CI: 0.375–0.672), more than one complication (HR = 0.381, 95% CI: 0.177–0.816), hypertension (HR = 0.611, 95% CI: 0.486–0.769), dyslipidemia (HR = 0.609, 95% CI: 0.450–0.824), cardiovascular disease (HR = 0.670, 95% CI: 0.458–0.979) and hospital patient being treated (HR = 1.273, 95% CI: 1.052–1.541). CONCLUSIONS: Median time to first optimal glycaemic control among T2DM patients is longer than expected which might imply that patients are being exposed to more risk of complication and death.
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spelling pubmed-66687942019-08-06 Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia Leulseged, Tigist W. Ayele, Birhanu T. PLoS One Research Article AIM: To estimate time to first optimal glycaemic control and identify prognostic factors among type 2 diabetes mellitus (T2DM) patients attending diabetes clinic of public teaching hospitals in Addis Ababa, Ethiopia. METHODS: A retrospective chart review study was conducted at diabetes clinic of Addis Ababa’s public teaching hospitals among a randomly selected sample of 685 charts of patients with T2DMwho were on follow up from January 1, 2013 to June 30, 2017. Data was collected using data abstraction tool. Descriptive statistics, Kaplan Meier plots, median survival time, Log-rank test and Cox proportional hazard survival models were used for analysis. RESULTS: Median time to first optimal glycaemic control among the study population was 9.5 months. Factors that affect time to first optimal glycaemic control were age group (HR = 0.635, 95% CI: 0.486–0.831 for 50–59 years, HR = 0.558, 95% CI: 0.403–0.771for 60–69 years and HR = 0.495, 95% CI: 0.310–0.790 for > = 70 years), diabetes neuropathy (HR = 0.502, 95% CI: 0.375–0.672), more than one complication (HR = 0.381, 95% CI: 0.177–0.816), hypertension (HR = 0.611, 95% CI: 0.486–0.769), dyslipidemia (HR = 0.609, 95% CI: 0.450–0.824), cardiovascular disease (HR = 0.670, 95% CI: 0.458–0.979) and hospital patient being treated (HR = 1.273, 95% CI: 1.052–1.541). CONCLUSIONS: Median time to first optimal glycaemic control among T2DM patients is longer than expected which might imply that patients are being exposed to more risk of complication and death. Public Library of Science 2019-07-31 /pmc/articles/PMC6668794/ /pubmed/31365544 http://dx.doi.org/10.1371/journal.pone.0220309 Text en © 2019 Leulseged, Ayele http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Leulseged, Tigist W.
Ayele, Birhanu T.
Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title_full Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title_fullStr Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title_full_unstemmed Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title_short Time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in Addis Ababa, Ethiopia
title_sort time to optimal glycaemic control and prognostic factors among type 2 diabetes mellitus patients in public teaching hospitals in addis ababa, ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668794/
https://www.ncbi.nlm.nih.gov/pubmed/31365544
http://dx.doi.org/10.1371/journal.pone.0220309
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