Cargando…
LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation
The Hippo pathway directs cell differentiation during organogenesis, in part by restricting proliferation. How Hippo signaling maintains a proliferation-differentiation balance in developing tissues via distinct molecular targets is only beginning to be understood. Our study makes the unexpected fin...
Autores principales: | Braitsch, Caitlin M., Azizoglu, D. Berfin, Htike, Yadanar, Barlow, Haley R., Schnell, Ulrike, Chaney, Christopher P., Carroll, Thomas J., Stanger, Ben Z., Cleaver, Ondine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668837/ https://www.ncbi.nlm.nih.gov/pubmed/31323030 http://dx.doi.org/10.1371/journal.pbio.3000382 |
Ejemplares similares
-
Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis
por: Azizoglu, D. Berfin, et al.
Publicado: (2017) -
Building Blood Vessels—One Rho GTPase at a Time
por: Barlow, Haley Rose, et al.
Publicado: (2019) -
Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation
por: Luo, Peter M., et al.
Publicado: (2023) -
miR-103 promotes the metastasis and EMT of hepatocellular carcinoma by directly inhibiting LATS2
por: Han, Li-Li, et al.
Publicado: (2018) -
Annexin A3 Regulates Early Blood Vessel Formation
por: Meadows, Stryder M., et al.
Publicado: (2015)