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Incapacitating solar urticaria: successful treatment with omalizumab

Solar urticaria is a rare form of physical urticaria mediated by immunoglobulin E. The lesions appear immediately after the sun exposure, interfering with the patient's normal daily life. Omalizumab, a monoclonal anti-IgE antibody, has been recently approved for the treatment of chronic spontan...

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Autores principales: Kieselova, Katarina, Santiago, Felicidade, Henrique, Martinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668931/
https://www.ncbi.nlm.nih.gov/pubmed/31365663
http://dx.doi.org/10.1590/abd1806-4841.20198109
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author Kieselova, Katarina
Santiago, Felicidade
Henrique, Martinha
author_facet Kieselova, Katarina
Santiago, Felicidade
Henrique, Martinha
author_sort Kieselova, Katarina
collection PubMed
description Solar urticaria is a rare form of physical urticaria mediated by immunoglobulin E. The lesions appear immediately after the sun exposure, interfering with the patient's normal daily life. Omalizumab, a monoclonal anti-IgE antibody, has been recently approved for the treatment of chronic spontaneous urticaria, and the latest reports support its role also in the treatment of solar urticaria. Hereby, we report a case of solar urticaria refractory to conventional treatment strategies, with an excellent response to treatment with omalizumab and phototesting normalization.
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spelling pubmed-66689312019-08-05 Incapacitating solar urticaria: successful treatment with omalizumab Kieselova, Katarina Santiago, Felicidade Henrique, Martinha An Bras Dermatol Case Report Solar urticaria is a rare form of physical urticaria mediated by immunoglobulin E. The lesions appear immediately after the sun exposure, interfering with the patient's normal daily life. Omalizumab, a monoclonal anti-IgE antibody, has been recently approved for the treatment of chronic spontaneous urticaria, and the latest reports support its role also in the treatment of solar urticaria. Hereby, we report a case of solar urticaria refractory to conventional treatment strategies, with an excellent response to treatment with omalizumab and phototesting normalization. Sociedade Brasileira de Dermatologia 2019 /pmc/articles/PMC6668931/ /pubmed/31365663 http://dx.doi.org/10.1590/abd1806-4841.20198109 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Case Report
Kieselova, Katarina
Santiago, Felicidade
Henrique, Martinha
Incapacitating solar urticaria: successful treatment with omalizumab
title Incapacitating solar urticaria: successful treatment with omalizumab
title_full Incapacitating solar urticaria: successful treatment with omalizumab
title_fullStr Incapacitating solar urticaria: successful treatment with omalizumab
title_full_unstemmed Incapacitating solar urticaria: successful treatment with omalizumab
title_short Incapacitating solar urticaria: successful treatment with omalizumab
title_sort incapacitating solar urticaria: successful treatment with omalizumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668931/
https://www.ncbi.nlm.nih.gov/pubmed/31365663
http://dx.doi.org/10.1590/abd1806-4841.20198109
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