ERα is required for suppressing OCT4‐induced proliferation of breast cancer cells via DNMT1/ISL1/ERK axis

OBJECTIVE: POU5F1 (OCT4) is implicated in cancer stem cell self‐renewal. Currently, some studies have shown that OCT4 has a dual function in suppressing or promoting cancer progression. However, the precise molecular mechanism of OCT4 in breast cancer progression remains unclear. MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales: Jin, Xiangshu, Li, Yanru, Guo, Yantong, Jia, Yiyang, Qu, Huinan, Lu, Yan, Song, Peiye, Zhang, Xiaoli, Shao, Yijia, Qi, Da, Xu, Wenhong, Quan, Chengshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668970/
https://www.ncbi.nlm.nih.gov/pubmed/31012189
http://dx.doi.org/10.1111/cpr.12612

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