Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90(+) skeletal stem cells in fracture sites

Cyclooxygenase 2 (COX-2) is essential for normal tissue repair. Although COX-2 is known to enhance the differentiation of mesenchymal stem cells (MSCs), how COX-2 regulates MSC differentiation into different tissue-specific progenitors to promote tissue repair remains unknown. Because it has been sh...

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Detalles Bibliográficos
Autores principales: Wasnik, Samiksha, Lakhan, Ram, Baylink, David J., Rundle, Charles H., Xu, Yi, Zhang, Jintao, Qin, Xuezhong, Lau, Kin-Hing William, Carreon, Edmundo E., Tang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669009/
https://www.ncbi.nlm.nih.gov/pubmed/31392271
http://dx.doi.org/10.1126/sciadv.aaw2108

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