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ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and disease. As such, they regulate cancer cell invasion, dissemination and metastasis of solid tumors. In addition, their expression is associated...

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Detalles Bibliográficos
Autores principales:	Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S., De Medts, Jelle, T’Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J., Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669144/ https://www.ncbi.nlm.nih.gov/pubmed/30679322 http://dx.doi.org/10.3324/haematol.2018.207837

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